MASSACHUSETTS - Greater Boston and Cambridge

From Connecticut, New York City and points south:

Take I-95 north, to I-93 north, which will take you into the heart of Boston.

From Western and Central Massachusetts, Upstate New York and points west:

Pick up I-90 east and take it directly into Boston.

From inland New Hampshire, Vermont and points north:

Take I-93 south directly into Boston.

From Coastal Maine, coastal New Hampshire and the Maritimes:

Take I-95 south, and pick up I-93 south into Boston.

From Cape Cod:

Take U.S. Route 6 west, to Mass Route 3 north, to I-93 north into Boston.